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We are seeking a motivated and skilled scientist to lead and support
organ chip research projects focused on modeling neurodevelopment and
evaluating the effects of nutritional components. The ideal candidate will have
a strong background in developmental neuroscience, organoid culture, and
microphysiological systems.
Key Responsibilities:

• Independently
  design and execute organoid/organ chip-based research projects related to
  brain development, including modeling of neuronal, glial, and blood-brain
  barrier (BBB) compartments.
• Develop and
  optimize protocols for the differentiation and co-culture of iPSC-derived
  neurons, microglia, astrocytes, and/or BBB components.
• Establish 3D
  neurodevelopmental models and evaluate the impact of nutritional compounds
  (e.g., DHA, HMOs, prebiotics, micronutrients) on neuronal maturation,
  synaptogenesis, inflammation, and functional connectivity.
• Implement
  cellular, molecular, and functional assays (e.g., immunostaining, qPCR,
  cytokine profiling, calcium imaging, multi-electrode array recording) to
  assess organoid responses to nutritional interventions.
• Contribute to
  the development of a functional screening platform for evaluating the
  efficacy of bioactive nutritional components.
• Coordinate
  project progress, ensure high-quality data collection and analysis, and
  participate in manuscript and report writing in both Chinese and English.

Preferred Qualifications:

• PhD or
  equivalent in Neuroscience, Developmental Biology, Biomedical Engineering,
  or related fields.
• Experience with
  human iPSC culture and neural differentiation is essential.
• Familiarity
  with organ-on-a-chip systems or advanced 3D culture models.
• Knowledge of
  nutritional neuroscience, gut-brain axis, or neuroinflammation is a strong
  plus.
• Proven ability
  to manage and execute multidisciplinary research projects.
• Excellent
  communication skills and scientific writing ability in both English and
  Chinese.

崗位描述：神經(jīng)科學(xué)方向科研人員——用于營(yíng)養(yǎng)神經(jīng)發(fā)育研究的類器官/器官芯片模型
我們正在招聘一位積極進(jìn)取、具備扎實(shí)科研能力的科研人員，主導(dǎo)和參與器官芯片相關(guān)研究項(xiàng)目，重點(diǎn)聚焦于神經(jīng)發(fā)育模型的構(gòu)建及營(yíng)養(yǎng)成分對(duì)其影響的機(jī)制研究。理想候選人應(yīng)具備神經(jīng)發(fā)育、生物工程或類器官培養(yǎng)等相關(guān)背景。
崗位職責(zé)：

• 獨(dú)立設(shè)計(jì)并執(zhí)行基于類器官/器官芯片的神經(jīng)發(fā)育相關(guān)研究項(xiàng)目，包括神經(jīng)元、膠質(zhì)細(xì)胞和血腦屏障等模塊的建模；
• 建立并優(yōu)化人源iPSC分化為神經(jīng)元、小膠質(zhì)細(xì)胞、星形膠質(zhì)細(xì)胞及血腦屏障等細(xì)胞類型的培養(yǎng)和共培養(yǎng)體系；
• 構(gòu)建三維神經(jīng)發(fā)育模型，系統(tǒng)評(píng)估營(yíng)養(yǎng)成分（如DHA、人乳低聚糖、益生元、微量元素等）對(duì)神經(jīng)發(fā)育過(guò)程中的成熟、突觸形成、炎癥反應(yīng)及功能連接的影響；
• 應(yīng)用細(xì)胞與分子生物學(xué)方法（如免疫染色、qPCR、細(xì)胞因子分析、鈣成像、多電極陣列記錄等）評(píng)估類器官對(duì)營(yíng)養(yǎng)干預(yù)的反應(yīng)；
• 參與營(yíng)養(yǎng)功能成分的篩選平臺(tái)開(kāi)發(fā)，推動(dòng)其在功能驗(yàn)證中的應(yīng)用；
• 協(xié)調(diào)項(xiàng)目進(jìn)展，確保高質(zhì)量數(shù)據(jù)收集與分析，撰寫(xiě)項(xiàng)目報(bào)告與中英文科研論文。

任職要求：

• 擁有神經(jīng)科學(xué)、發(fā)育生物學(xué)、生物醫(yī)學(xué)工程或相關(guān)專業(yè)的博士學(xué)位；
• 具有人源iPSC培養(yǎng)及神經(jīng)分化經(jīng)驗(yàn)；
• 熟悉類器官/器官芯片系統(tǒng)或先進(jìn)三維培養(yǎng)技術(shù)；
• 具有營(yíng)養(yǎng)神經(jīng)科學(xué)、腸-腦軸或神經(jīng)炎癥研究經(jīng)驗(yàn)者優(yōu)先；
• 具備良好的項(xiàng)目管理和跨學(xué)科協(xié)作能力；
• 具備優(yōu)秀的中英文溝通能力和科研寫(xiě)作能力。